Evaluation Manuals

The Evaluation Manual is a technical instructions and gives information on assessment standards, assessment framework, and calculation models that are used to conduct the assessments.

Ctgb developed a special evaluation manual for Biopesticides; below you will find the EM for conventional PPP.

Evaluation Manual – version 2.1/2.2/2.3-E: the latest version

The Evaluation Manual describes the assessment framework used by the Ctgb for the assessment of applications for authorization of plant protection products. Data requirements, risk assessment methodologies and approval criteria are discussed in the Evaluation Manual, which combines the collective context of laws and regulations, policies, and the guidance documents that describe the methodology for assessment of plant protection products and active substances. The Evaluation Manual presents the European evaluation framework, with an additional section on the national framework. Requirements related to Dutch specific elements are listed in the latter section.

The manuals are periodically updated in accordance with new legislation and guidances. They are published in English. In this version of the Evaluation Manual for each chapter a change log is added in which the adjustments in comparison to the previous version are disclosed. In the manuals reference is made to external sources by hyperlinks.

Version 2.1/2.2/2.3-E, published in September 2018.

EU Evaluation framework and national parts:

  1. General Introduction
  2. Physical-Chemical properties
  3. Analytical Methods
  4. Human Toxicology
  5. Residues
  6. Environmental Fate & Behaviour
  7. Ecotoxicology
  8. Efficacy

Previous versions of the Evaluation manual

Version Control

Version control

EU Chapters

Oct'16

Mar'17

Apr'17

Nov'17

Jan'18

Feb'18

Apr'18

May'18

July '18

Sep'18

1. General introduction and Genneric aspects Version 2.1 Version 2.2 Version 2.3
2. Physical chemical properties Version 2.1
3. Analytical Methods Version 2.1
4. Human toxicology; mammalian toxicology Version 2.1  Version 2.2 Version 2.3
4. Human toxicology; risk operator, worker, bystander and resident  Version 2.1  Version 2.2
5. Residues; residue dossier Version 2.1 Version 2.2 Version 2.3
5. Residues; risk consumer Version 2.1 Version 2.2 Version 2.3
6. Fate and behaviour in the environment; behaviour in soil; persistence Version 2.1 Version 2.2
6. Fate and behaviour in the environment; behaviour in soil; leaching Version 2.1 Version 2.2
6. Fate and behaviour in the environment; behaviour in
surface water, sediment and sewage treatment plants (STP)
Version 2.1 Version 2.2
6. Fate and behaviour in the environment; behaviour in air Version 2.1
7. Ecotoxicology; aquatic Version 2.1
7. Ecotoxicology; terrestrial; bees Version 2.1
7. Ecotoxicology; terrestrial; birds and mammals Version 2.1 Version 2.2 Version 2.3
7. Ecotoxicology; terrestrial; soil organisms Version 2.1 Version 2.2
7. Ecotoxicology; terrestrial; non target arthropods and plants Version 2.1
7. Ecotoxicology; appendix A; combination toxicity Version 2.1
8. Efficacy Version 2.1

NL Chapters

Oct'16

Mar'17

Apr'17

Nov'17

Jan'18

Feb'18

Apr'18

May'18

July'18

Sep'18

1. General introduction and Genneric aspects Version 2.1
2. Physical chemical properties Version 2.1
3. Analytical Methods Version 2.1
4. Human toxicology; risk operator, worker and bystander Version 2.1  Version 2.2
Appendix 1 to chapter 4 Human toxicology;
Risk operator, worker and bystander; field use scenario list
Version 2.1 Version 2.2
5. Residues; residue dossier Version 2.1
5. Residues; risk consumer Version 2.1
6. Fate and behaviour in the environment; behaviour in soil; persistence Version 2.1
6. Fate and behaviour in the environment; behaviour in soil; leaching Version 2.1 Version 2.2 Version 2.3
6. Fate and behaviour in the environment; behaviour in
surface water, sediment and sewage treatment plants (STP)
Version 2.1 Version 2.2 Version 2.3
6. Fate and behaviour in the environment; behaviour in air Version 2.1
7. Ecotoxicology; aquatic Version 2.1 Version 2.2
7. Ecotoxicology; terrestrial; bees Version 2.1 Version 2.2
7. Ecotoxicology; terrestrial; birds and mammals Version 2.1
7. Ecotoxicology; terrestrial; soil organisms Version 2.1
7. Ecotoxicology; terrestrial; non target arthropods and plants Version 2.1 Version 2.2
8. Efficacy Version 2.1 Version 2.2
8. Efficacy; crop definition DTG v 2.1 Version 2.1
8. Efficacy; was wordt lijst DTG v 2.0 naar DTG2.1 Version 2.1
8. Efficacy; crop definition DTG 2.0 Version 2.1
8. Efficacy; crop cycle list NL/Eng Version 2.1
8. Efficacy; DTW lijst v 2.0 Version 2.1
8. Efficacy; spray volume list v 2.0 Version 2.1
8. Efficacy; dipping fluid up take by flower bulbs Version 2.1
8. Efficacy; extrapolation document Version 2.1
8. Efficacy; Sowing denities list (in Dutch) Version 2.1
Version number V 2.1  V 2.1/2.2-A V 2.1/2.2-B V 2.1/2.2-C V 2.1/2.2-D V 2.1/2.2/2.3-A V 2.1/2.2/2.3-B V 2.1/2.2/2.3-C V 2.1/2.2/2.3-D V 2.1/2.2/2.3-E