The CLP Regulation (1272/2008) concerns the Classification, Labelling and Packaging of chemical substances and mixtures.

Changes to the list are periodically necessary due to technical and scientific progress. Since Regulation 1272/2008 went into force in 2009, the appendices (the ATPs) have undergone various changes. This concerns changes in the classification, labelling and packaging requirements, as well as changes in the harmonised classification of substances in Appendix VI. Authorisation holders are obligated to keep track of such changes that may affect their authorised products, and if necessary request an amendment of the corresponding label from the Ctgb.

The ECHA website present more information on CLP: